alpha Fetoprotein Antikörper

Produktnummer ABIN969492

Zitiert in 2+ Publikationen. Der Maus Monoklonal anti-alpha Fetoprotein Antikörper (Klon 6E6) (ABIN969492) detektiert spezifisch alpha Fetoprotein in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für alpha Fetoprotein Antikörper (ABIN969492)

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser alpha Fetoprotein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 6E6

Produktdetails anti-alpha Fetoprotein Antikörper

Verwendungszweck: AFP Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human AFP expressed in E. Coli.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-alpha Fetoprotein Antikörper (ABIN969492)

Noda, Miyoshi, Kitada, Nakahara, Gao, Honke, Shiratori, Moriwaki, Sasaki, Kasahara, Hori, Hayashi, Taniguchi: "The enzymatic basis for the conversion of nonfucosylated to fucosylated alpha-fetoprotein by acyclic retinoid treatment in human hepatoma cells: activation of alpha1-6 fucosyltransferase." in: Tumour biology, Vol. 23, Issue 4, pp. 202-11, (2002) (PubMed).

Sayar, Yaniv, Goshen, Cohen: "Treatment of alpha-fetoprotein secreting hepatoblastoma by response of serum alpha-fetoprotein levels: a new concept." in: Pediatric hematology and oncology, Vol. 18, Issue 8, pp. 509-18, (2001) (PubMed).

Details zu alpha Fetoprotein

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Andere Bezeichnung: AFP

Hintergrund: AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Molekulargewicht: 69 kDa

Gen-ID: 174

UniProt: P02771

Pathways: C21-Steroid Hormone Metabolic Process