ZBTB16 Antikörper

Produktnummer ABIN969465

Dieses Anti-ZBTB16-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ZBTB16 in WB, ELISA und ICC. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für ZBTB16 Antikörper (ABIN969465)

Target: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ZBTB16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Klon: 5B3

Produktdetails anti-ZBTB16 Antikörper

Verwendungszweck: ZBTB16 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human ZBTB16 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-ZBTB16 Antikörper (ABIN969465)

Felicetti, Errico, Bottero, Segnalini, Stoppacciaro, Biffoni, Felli, Mattia, Petrini, Colombo, Peschle, Carè: "The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms." in: Cancer research, Vol. 68, Issue 8, pp. 2745-54, (2008) (PubMed).

Details zu ZBTB16

Target: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Andere Bezeichnung: ZBTB16

Hintergrund: This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. Tissue specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.

Molekulargewicht: 74 kDa

UniProt: Q05516

Pathways: Positive Regulation of fat Cell Differentiation