Synaptophysin Antikörper

Produktnummer ABIN969428

Der Maus Monoklonal Anti-Synaptophysin-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, Synaptophysin in Proben von Human und Ratte zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für Synaptophysin Antikörper (ABIN969428)

Target: Synaptophysin (SYP)

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Synaptophysin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 7H12

Produktdetails anti-Synaptophysin Antikörper

Verwendungszweck: SYP Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of SYP expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Synaptophysin Antikörper (ABIN969428)

Gulubova, Vlaykova: "Chromogranin A-, serotonin-, synaptophysin- and vascular endothelial growth factor-positive endocrine cells and the prognosis of colorectal cancer: an immunohistochemical and ultrastructural study." in: Journal of gastroenterology and hepatology, Vol. 23, Issue 10, pp. 1574-85, (2009) (PubMed).

Sterlacci, Fiegl, Hilbe, Auberger, Mikuz, Tzankov: "Clinical relevance of neuroendocrine differentiation in non-small cell lung cancer assessed by immunohistochemistry: a retrospective study on 405 surgically resected cases." in: Virchows Archiv : an international journal of pathology, Vol. 455, Issue 2, pp. 125-32, (2009) (PubMed).

Xu, Dai, Xiang, Zhao, Ruan, Cheng, Zheng, Shu: "Nutritional factors in relation to endometrial cancer: a report from a population-based case-control study in Shanghai, China." in: International journal of cancer. Journal international du cancer, Vol. 120, Issue 8, pp. 1776-81, (2007) (PubMed).

Details zu Synaptophysin

Target: Synaptophysin (SYP)

Andere Bezeichnung: SYP

Hintergrund: Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.

Molekulargewicht: 33.8 kDa

Gen-ID: 6855

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity