SND1 Antikörper (AA 361-485)

Produktnummer ABIN969411

Dieses Anti-SND1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von SND1 in WB und ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für SND1 Antikörper (AA 361-485) (ABIN969411)

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SND1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 2D7

Produktdetails anti-SND1 Antikörper

Bindungsspezifität: AA 361-485

Verwendungszweck: SND1/P100 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of SND1 (aa361-485) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-SND1 Antikörper (ABIN969411)

Broadhurst, Lee, Hawkins, Wheeler: "The p100 EBNA-2 coactivator: a highly conserved protein found in a range of exocrine and endocrine cells and tissues in cattle." in: Biochimica et biophysica acta, Vol. 1681, Issue 2-3, pp. 126-33, (2005) (PubMed).

Tijms, Snijder: "Equine arteritis virus non-structural protein 1, an essential factor for viral subgenomic mRNA synthesis, interacts with the cellular transcription co-factor p100." in: The Journal of general virology, Vol. 84, Issue Pt 9, pp. 2317-22, (2003) (PubMed).

Details zu SND1

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Andere Bezeichnung: SND1/P100

Hintergrund: SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, it functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activatior of EBNA-2. It also interacts with EAV, NSP1,GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.

Molekulargewicht: 102 kDa

UniProt: Q7KZF4