S100B Antikörper

Produktnummer ABIN969391

Dieses Maus Monoklonal-Antikörper erkennt spezifisch S100B in IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für S100B Antikörper (ABIN969391)

Target: S100B (S100 Calcium Binding Protein B (S100B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser S100B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Klon: 9A11B9

Produktdetails anti-S100B Antikörper

Verwendungszweck: S100B Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of S100B expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-S100B Antikörper (ABIN969391)

Zimmer, Chaplin, Baldwin, Rast: "S100-mediated signal transduction in the nervous system and neurological diseases." in: Cellular and molecular biology (Noisy-le-Grand, France), Vol. 51, Issue 2, pp. 201-14, (2005) (PubMed).

Sorci, Riuzzi, Arcuri, Giambanco, Donato: "Amphoterin stimulates myogenesis and counteracts the antimyogenic factors basic fibroblast growth factor and S100B via RAGE binding." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4880-94, (2004) (PubMed).

Shapiro, Marks, Whitaker-Azmitia: "Increased clusterin expression in old but not young adult S100B transgenic mice: evidence of neuropathological aging in a model of Down Syndrome." in: Brain research, Vol. 1010, Issue 1-2, pp. 17-21, (2004) (PubMed).

Details zu S100B

Target: S100B (S100 Calcium Binding Protein B (S100B))

Andere Bezeichnung: S100B

Hintergrund: S100B (S100 calcium binding protein B) is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S100B are present in a variety of other tissues, and calbindin is present in intestine and kidney. Parvalbumin B is found in many tumor tissues as well as in the organ of Corti. Calbindin, S-100 proteins and parvalbulmins have all been detected in leydig cells and the testis. These proteins are thought to play a role in hormone production and spermatogenesis. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Gen-ID: 6285

UniProt: P04271

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine