PTH1R Antikörper

Produktnummer ABIN969372

Dieses Anti-PTH1R-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PTH1R in IHC, ELISA und ICC. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für PTH1R Antikörper (ABIN969372)

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PTH1R Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Klon: 4D2

Produktdetails anti-PTH1R Antikörper

Verwendungszweck: PTH1R Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human PTH1R expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-PTH1R Antikörper (ABIN969372)

Dean, Vilardaga, Potts, Gardella: "Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor." in: Molecular endocrinology (Baltimore, Md.), Vol. 22, Issue 1, pp. 156-66, (2007) (PubMed).

Yang, Hoang, Kubo, Kawano, Chou, Sowers, Huvos, Meyers, Healey, Gorlick: "Over-expression of parathyroid hormone Type 1 receptor confers an aggressive phenotype in osteosarcoma." in: International journal of cancer. Journal international du cancer, Vol. 121, Issue 5, pp. 943-54, (2007) (PubMed).

Details zu PTH1R

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Andere Bezeichnung: PTH1R

Hintergrund: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

Molekulargewicht: 66 kDa

Gen-ID: 5745

UniProt: Q03431

Pathways: Regulation of Carbohydrate Metabolic Process