PKN2 Antikörper

Produktnummer ABIN969363

Dieses Anti-PKN2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PKN2 in WB, IHC, ELISA und FACS. Geeignet für Human, Maus, Ratte und Affe. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für PKN2 Antikörper (ABIN969363)

Target: PKN2 (Protein Kinase N2 (PKN2))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PKN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Klon: 1D1

Produktdetails anti-PKN2 Antikörper

Verwendungszweck: PRK2 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human PRK2 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-PKN2 Antikörper (ABIN969363)

Cornelis, Qi, Zhang, Kraft, Manson, Cai, Hunter, Hu: "Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry." in: Annals of internal medicine, Vol. 150, Issue 8, pp. 541-50, (2009) (PubMed).

Details zu PKN2

Target: PKN2 (Protein Kinase N2 (PKN2))

Andere Bezeichnung: PRK2

Hintergrund: Protein-kinase-C-related kinases (PRKs) are part of the lipid-regulated protein kinases (PKC) which also include liver PAK & PKN. Human PRK1 and PRK2 share structurally similar catalytic domains, but less similar N-terminal regulatory regions suggesting different regulatory domain functions. PRK1 and PRK2, as well as a third member of this family, PRK3, show distinct patterns of expression in adult tissues. Additionally, the serine-threonine kinase PRK2 can be specifically cleaved by caspase-3 (and/or caspase-3-like subfamily members) during apoptosis.

Molekulargewicht: 140 kDa

Gen-ID: 5586

UniProt: Q16513

Pathways: Cell-Cell Junction Organization