PGA5 Antikörper

Produktnummer ABIN969350

Der Maus Monoklonal Anti-PGA5-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, PGA5 in Proben von Human zu detektieren.

Kurzübersicht für PGA5 Antikörper (ABIN969350)

Target: PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PGA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 2C1

Produktdetails anti-PGA5 Antikörper

Verwendungszweck: PGA5 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human PGA5 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu PGA5

Target: PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))

Andere Bezeichnung: PGA5

Hintergrund: PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity ( pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.

Molekulargewicht: 42 kDa

Gen-ID: 5222

UniProt: P0DJD9