p63alpha Antikörper
Kurzübersicht für p63alpha Antikörper (ABIN969337)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- p63a Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Synthesized peptide of human p63alpha.
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Isotyp
- IgG1
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "The p53 homologue DeltaNp63alpha interacts with the nuclear factor-kappaB pathway to modulate epithelial cell growth." in: Cancer research, Vol. 68, Issue 13, pp. 5122-31, (2008) (PubMed).
: "R298Q mutation of p63 gene in autosomal dominant ectodermal dysplasia associated with arrhythmogenic right ventricular cardiomyopathy." in: European journal of medical genetics, Vol. 51, Issue 5, pp. 497-500, (2008) (PubMed).
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- p63alpha
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Andere Bezeichnung
- p63a
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Hintergrund
- The p63 gene is a homologue of the p53 tumor suppressor gene. Like p53, p63 contains a transactivation (TA) domain induce the transcription of target genes, a DNA binding domain, and an oligomerization domain (OD), used to form tetramers. In contrast to p53, the p63 gene encodes for at least six major isotypes. Three isotypes (TAp63a, TAp63
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Molekulargewicht
- 51 kDa
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Gen-ID
- 8626
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UniProt
- Q9H3D4
Target
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