MTHFR Antikörper

Produktnummer ABIN969297

Produktdetails anti-MTHFR Antikörper

Target: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MTHFR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human MTHFR expressed in E. coli.

Klon: 5D3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-MTHFR Antikörper (ABIN969297)

Sarecka-Hujar, Zak, Krauze: "Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease." in: Kardiologia polska, Vol. 66, Issue 12, pp. 1269-77, (2009) (PubMed).

Oliveira, Bianco, Bianco, Verreschi, Guedes, Galera, Galera, Barbosa, Lipay: "Prevalence of the polymorphism MTHFR A1298C and not MTHFR C677T is related to chromosomal aneuploidy in Brazilian Turner Syndrome patients." in: Arquivos brasileiros de endocrinologia e metabologia, Vol. 52, Issue 8, pp. 1374-81, (2009) (PubMed).

Details zu MTHFR

Target: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Andere Bezeichnung: MTHFR (MTHFR Produkte)

Synonyme: DDBDRAFT_0204686 antikoerper, DDBDRAFT_0230137 antikoerper, DDB_0204686 antikoerper, DDB_0230137 antikoerper, AI323986 antikoerper, methylenetetrahydrofolate reductase (NAD(P)H) L homeolog antikoerper, methylenetetrahydrofolate reductase antikoerper, methylenetetrahydrofolate reductase (NAD(P)H) antikoerper, 5,10-methylenetetrahydrofolate reductase antikoerper, mthfr.L antikoerper, MTHFR antikoerper, mthfr antikoerper, metF antikoerper, DDB_G0279137 antikoerper, Mthfr antikoerper

Hintergrund:

Description: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Aliases: MTHFR

Molekulargewicht: 75 kDa

Gen-ID: 4524

HGNC: 4524

Pathways: Methionine Biosynthetic Process