Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

KLHL13 Antikörper

KLHL13 Reaktivität: Human WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 8D1 unconjugated
Produktnummer ABIN969245
  • Target Alle KLHL13 Antikörper anzeigen
    KLHL13 (Kelch-Like 13 (KLHL13))
    Reaktivität
    • 16
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 23
    • 8
    Maus
    Klonalität
    • 23
    • 8
    Monoklonal
    Konjugat
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KLHL13 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 13
    • 13
    • 7
    • 7
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human KLHL13 expressed in E. coli.
    Klon
    8D1
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Jin, Pahuja, Wickliffe, Gorur, Baumgärtel, Schekman, Rape: "Ubiquitin-dependent regulation of COPII coat size and function." in: Nature, Vol. 482, Issue 7386, pp. 495-500, (2012) (PubMed).

    Suzuki, Yamashita, Shirota, Sakakibara, Chiba, Mizushima-Sugano, Nakai, Sugano: "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions." in: Genome research, Vol. 14, Issue 9, pp. 1711-8, (2004) (PubMed).

  • Target
    KLHL13 (Kelch-Like 13 (KLHL13))
    Andere Bezeichnung
    KLHL13 (KLHL13 Produkte)
    Synonyme
    1200009K10Rik antikoerper, AI451128 antikoerper, Bklhd2 antikoerper, D130072F20Rik antikoerper, mKIAA1309 antikoerper, BKLHD2 antikoerper, Kelch-like protein 13 antikoerper, kelch-like 13 antikoerper, kelch like family member 13 antikoerper, kelch like family member 9 antikoerper, kelch-like family member 13 antikoerper, klh13 antikoerper, Klhl13 antikoerper, KLHL13 antikoerper, KLHL9 antikoerper
    Hintergrund

    Description: KLHL13 (kelch-like 13), also known as BKLHD2 (BTB and kelch domain-containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate- specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Via its BTB and C-terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL-3 ligase.

    Aliases: BKLHD2, FLJ10262, MGC74791, KLHL13

    Molekulargewicht
    74 kDa
    Gen-ID
    90293
    HGNC
    90293
Sie sind hier:
Kundenservice