KLHL1 Antikörper

Produktnummer ABIN969241

Dieses Maus Monoklonal-Antikörper erkennt spezifisch KLHL1 in ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für KLHL1 Antikörper (ABIN969241)

Target: KLHL1 (Kelch-Like 1 (KLHL1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KLHL1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC)

Klon: 3A8

Produktdetails anti-KLHL1 Antikörper

Verwendungszweck: KLHL1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human KLHL1 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-KLHL1 Antikörper (ABIN969241)

Barrios-Rodiles, Brown, Ozdamar, Bose, Liu, Donovan, Shinjo, Liu, Dembowy, Taylor, Luga, Przulj, Robinson, Suzuki, Hayashizaki, Jurisica, Wrana: "High-throughput mapping of a dynamic signaling network in mammalian cells." in: Science (New York, N.Y.), Vol. 307, Issue 5715, pp. 1621-5, (2005) (PubMed).

Details zu KLHL1

Target: KLHL1 (Kelch-Like 1 (KLHL1))

Andere Bezeichnung: KLHL1

Hintergrund: The mammalian Kelch like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved in this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.Tissue specificity: Highly expressed in brain.

Molekulargewicht: 82 kDa

Gen-ID: 57626

UniProt: Q9NR64