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ICAM1 Antikörper (AA 28-480)

Name: ICAM1 Antikörper (AA 28-480)
Brand: antibodies-online
SKU: ABIN969206
Price: 562.94 EUR
Availability: InStock

ICAM1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 6G12 unconjugated

Western blot analysis using ICAM1 mouse mAb against ICAM1(AA: 28-480)-hIgGFc transfected HEK293 (1) cell lysate. (ICAM1 Antikörper (AA 28-480))

1 image

(1 reference)

Produktnummer ABIN969206

Datenblatt (PDF)

Target Alle ICAM1 Antikörper anzeigen

ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
Bindungsspezifität
18

16

16

8

7

6

5

4

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 28-480
Reaktivität
215

82

38

7

5

4

4

3

1

1
Human
Wirt
117

117

28

3

2

1

1

1
Maus
Passende Sekundärantikörper
Klonalität
148

119

1
Monoklonal
Konjugat
117

24

24

20

14

6

5

5

4

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Dieser ICAM1 Antikörper ist unkonjugiert
Applikation
164

151

63

61

41

40

33

32

30

28

24

20

12

10

6

4

4

4

3

3

3

2

1

1

1

1

1
Western Blotting (WB), ELISA

Aufreinigung

purified

Immunogen

Purified recombinant fragment of human ICAM1(28-480aa) expressed in E. coli.

Klon

6G12

Isotyp

IgG1

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Applikationshinweise

ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

4°C, -20°C for long term storage
Yang, Cullen, Li, Chapman, Jewell: "Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1." in: Journal of hepatology, Vol. 40, Issue 3, pp. 375-9, (2004) (PubMed).
Target

ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Andere Bezeichnung

ICAM1 (ICAM1 Produkte)

Synonyme

BB2 antikoerper, CD54 antikoerper, P3.58 antikoerper, Icam-1 antikoerper, Ly-47 antikoerper, MALA-2 antikoerper, ICAM antikoerper, ICAM-1 antikoerper, ICAM1 antikoerper, intercellular adhesion molecule 1 antikoerper, intercellular adhesion molecule-1 antikoerper, ICAM1 antikoerper, Icam1 antikoerper, ICAM-1 antikoerper

Substanzklasse

Viral Protein

Hintergrund

Description: ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.
Aliases: BB2, CD54, P3.58, ICAM1

Molekulargewicht

57.8 kDa

Gen-ID

3383

HGNC

3383

Pathways

Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling