HPRT1 Antikörper

Produktnummer ABIN969197

Der Mouse Monoclonal Anti-HPRT1-Antikörper wurde für ELISA validiert. Er ist geeignet, HPRT1 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für HPRT1 Antikörper (ABIN969197)

Target: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HPRT1 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 1F8D11

Produktdetails anti-HPRT1 Antikörper

Verwendungszweck: HPRT Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of HPRT expressed in E. Coli.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-HPRT1 Antikörper (ABIN969197)

Manjanatha, Shelton, Bishop, Shaddock, Dobrovolsky, Heflich, Webb, Blankenship, Beland, Greenlees, Culp: "Analysis of mutations and bone marrow micronuclei in Big Blue rats fed leucomalachite green." in: Mutation research, Vol. 547, Issue 1-2, pp. 5-18, (2004) (PubMed).

Details zu HPRT1

Target: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Andere Bezeichnung: HPRT

Hintergrund: The HPRT1 gene provides instructions for making an enzyme called hypoxanthine phosphoribosyltransferase 1. This enzyme allows cells to recycle purines, some of the building blocks of DNA and its chemical cousin RNA.The enzyme hypoxanthine-guanine phosphoribosyltrasferase (E.C.2.4.2.8., HPRT) plays a crucial role in uric acid synthesis and purine metabolism.This enzyme catalyzes the conversion of hypoxanthine and guanine to inosine monophosphate (IMP) and guanosine monophosphate (GMP), respectively, and uses phosphoribosylpyrophosphate (PRPP) as a cosubstrate and as a source of energy . This pathway is also known as the purine salvage pathway because it allows cells to reuse purine compounds to build DNA and RNA.

UniProt: P00492

Pathways: Ribonucleoside Biosynthetic Process