Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

HAS1 Antikörper

HAS1 Reaktivität: Human WB, ELISA, ICC Wirt: Maus Monoclonal 3-00E-10 unconjugated
Produktnummer ABIN969185
  • Target Alle HAS1 Antikörper anzeigen
    HAS1 (Hyaluronan Synthase 1 (HAS1))
    Reaktivität
    • 49
    • 24
    • 23
    • 6
    • 6
    • 5
    • 2
    • 1
    Human
    Wirt
    • 45
    • 5
    Maus
    Klonalität
    • 45
    • 5
    Monoklonal
    Konjugat
    • 17
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HAS1 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 25
    • 20
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human HAS1 expressed in E. coli.
    Klon
    3-00E-10
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Stuhlmeier: "Hyaluronan production in synoviocytes as a consequence of viral infections: HAS1 activation by Epstein-Barr virus and synthetic double- and single-stranded viral RNA analogs." in: The Journal of biological chemistry, Vol. 283, Issue 24, pp. 16781-9, (2008) (PubMed).

    Adamia, Treon, Reiman, Tournilhac, McQuarrie, Mant, Belch, Pilarski: "Potential impact of a single nucleotide polymorphism in the hyaluronan synthase 1 gene in Waldenstrom's macroglobulinemia." in: Clinical lymphoma, Vol. 5, Issue 4, pp. 253-6, (2005) (PubMed).

  • Target
    HAS1 (Hyaluronan Synthase 1 (HAS1))
    Andere Bezeichnung
    HAS1 (HAS1 Produkte)
    Synonyme
    dg42 antikoerper, Xhas1 antikoerper, HAS antikoerper, shas1 antikoerper, hyaluronan synthase 1 antikoerper, hyaluronan synthase 1 S homeolog antikoerper, has1 antikoerper, HAS1 antikoerper, Has1 antikoerper, has1.S antikoerper
    Hintergrund

    Description: Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS1 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from Xenopus laevis, and a recently described murine hyaluronan synthase.

    Aliases: HAS, HAS1

    Molekulargewicht
    65 kDa
    Gen-ID
    3036
    HGNC
    3036
    Pathways
    Glycosaminoglycan Metabolic Process
Sie sind hier:
Kundenservice