GATA3 Antikörper

Produktnummer ABIN969168

Dieses Anti-GATA3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von GATA3 in ELISA und IHC. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für GATA3 Antikörper (ABIN969168)

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GATA3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Klon: 7B5

Produktdetails anti-GATA3 Antikörper

Verwendungszweck: GATA3 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human GATA3 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-GATA3 Antikörper (ABIN969168)

Muzzioli, Stecconi, Moresi, Provinciali: "Zinc improves the development of human CD34+ cell progenitors towards NK cells and increases the expression of GATA-3 transcription factor in young and old ages." in: Biogerontology, Vol. 10, Issue 5, pp. 593-604, (2009) (PubMed).

van Hamburg, Mus, de Bruijn, de Vogel, Boon, Cornelissen, Asmawidjaja, Hendriks, Lubberts: "GATA-3 protects against severe joint inflammation and bone erosion and reduces differentiation of Th17 cells during experimental arthritis." in: Arthritis and rheumatism, Vol. 60, Issue 3, pp. 750-9, (2009) (PubMed).

Details zu GATA3

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Andere Bezeichnung: GATA3

Hintergrund: This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. (provided by RefSeq) Tissue specificity: T-cells and endothelial cells RD: GATA-3 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. It is widely expressed in mesodermal- and endodermal-derived tissues. GATA-3 has been shown to be an essential regulator for immune cell function, sympathetic neuron development, and the maintenance of the differentiated state in epithelial cells.

Molekulargewicht: 48 kDa

Gen-ID: 2625

UniProt: P23771

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation