FMR1 Antikörper

Produktnummer ABIN969148

Dieser Maus Monoklonal Antikörper erkennt spezifisch FMR1 in IHC, ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FMR1 Antikörper (ABIN969148)

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FMR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Klon: 4G9

Produktdetails anti-FMR1 Antikörper

Verwendungszweck: FMR1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human FMR1 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Andere Bezeichnung: FMR1

Hintergrund: FMR1, also known as POF, FMRP, FRAXA. Entrez Protein: NP_002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.

Molekulargewicht: 71 kDa

Gen-ID: 2332

UniProt: Q06787

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development