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FABP2 Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch FABP2 in WB, IHC, ELISA, ICC und FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.
Produktnummer ABIN969124

Kurzübersicht für FABP2 Antikörper (ABIN969124)

Target

Alle FABP2 Antikörper anzeigen
FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Reaktivität

  • 60
  • 33
  • 29
  • 5
  • 3
  • 2
  • 1
Human

Wirt

  • 75
  • 21
  • 3
Maus

Klonalität

  • 75
  • 23
Monoklonal

Konjugat

  • 61
  • 15
  • 10
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FABP2 Antikörper ist unkonjugiert

Applikation

  • 80
  • 58
  • 33
  • 29
  • 21
  • 10
  • 8
  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon

9A9B7B3
  • Verwendungszweck

    FABP2 Antibody

    Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of human FABP2 expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Fisher, Li, Burwinkel, Kühr, Hoffmann, Möhlig, Spranger, Pfeiffer, Boeing, Schrezenmeir, Döring: "Preliminary evidence of FABP2 A54T polymorphism associated with reduced risk of type 2 diabetes and obesity in women from a German cohort." in: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, Vol. 38, Issue 5, pp. 341-5, (2006) (PubMed).

    Kim, Yun, Byun, Yoo, Lee, Suh: "Codon 54 polymorphism of the fatty acid binding protein 2 gene is associated with increased fat oxidation and hyperinsulinemia, but not with intestinal fatty acid absorption in Korean men." in: Metabolism: clinical and experimental, Vol. 50, Issue 4, pp. 473-6, (2001) (PubMed).

    Georgopoulos, Aras, Tsai: "Codon-54 polymorphism of the fatty acid-binding protein 2 gene is associated with elevation of fasting and postprandial triglyceride in type 2 diabetes." in: The Journal of clinical endocrinology and metabolism, Vol. 85, Issue 9, pp. 3155-60, (2000) (PubMed).

  • Target

    FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

    Andere Bezeichnung

    FABP2

    Hintergrund

    The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. Genetic variation in FABP2 may thus contribute to interindividual variation in the response of plasma lipoproteins to different dietary fibres, but the mechanism does not appear to be related to increases in fecal bile acid secretion.

    Molekulargewicht

    15 kDa

    Gen-ID

    2169

    UniProt

    P12104
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