Estrogen Receptor alpha Antikörper

Produktnummer ABIN969119

Produktdetails anti-Estrogen Receptor alpha Antikörper

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human ESR1 expressed in E. coli.

Klon: 6B6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Estrogen Receptor alpha Antikörper (ABIN969119)

Deegan, Seldeen, McDonald, Bhat, Farooq: "Binding of the ERalpha nuclear receptor to DNA is coupled to proton uptake." in: Biochemistry, Vol. 49, Issue 29, pp. 5978-88, (2010) (PubMed).

Harsløf, Husted, Carstens, Stenkjaer, Langdahl: "Genotypes and haplotypes of the estrogen receptor genes, but not the retinoblastoma-interacting zinc finger protein 1 gene, are associated with osteoporosis." in: Calcified tissue international, Vol. 87, Issue 1, pp. 25-35, (2010) (PubMed).

Details zu Estrogen Receptor alpha

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Andere Bezeichnung: ESR1 (ESR1 Produkte)

Synonyme: LOC398734 antikoerper, AA420328 antikoerper, AU041214 antikoerper, ER-alpha antikoerper, ER[a] antikoerper, ERa antikoerper, ERalpha antikoerper, ESR antikoerper, Estr antikoerper, Estra antikoerper, Nr3a1 antikoerper, NR3A1 antikoerper, eralpha antikoerper, zfER[a] antikoerper, ER antikoerper, ESRA antikoerper, ESTRR antikoerper, Era antikoerper, akap12 antikoerper, cb27 antikoerper, esr1 antikoerper, fb72g12 antikoerper, id:ibd1202 antikoerper, sb:cb27 antikoerper, si:ch73-192g21.1 antikoerper, wu:fb72g12 antikoerper, wu:fc21c03 antikoerper, Esr antikoerper, RNESTROR antikoerper, ERALPHA antikoerper, er antikoerper, esr antikoerper, nr3a1 antikoerper, XER antikoerper, era antikoerper, esra antikoerper, ERbeta antikoerper, xesr-1 antikoerper, xlERalpha1 antikoerper, xlERalpha2 antikoerper, ESR1 antikoerper, estrogen receptor 1 L homeolog antikoerper, estrogen receptor 1 (alpha) antikoerper, estrogen receptor 1 antikoerper, A kinase (PRKA) anchor protein 12b antikoerper, esr1.L antikoerper, Esr1 antikoerper, ESR1 antikoerper, esr1 antikoerper, akap12b antikoerper

Hintergrund:

Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.

Aliases: ER, ESR, Era, ESRA, NR3A1, DKFZp686N23123, ESR1

Molekulargewicht: 66 kDa

Gen-ID: 2099

HGNC: 2099

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly