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Estrogen Receptor alpha Antikörper (AA 130-339)

Dieses Anti-Estrogen Receptor alpha-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Estrogen Receptor alpha in ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN969117

Kurzübersicht für Estrogen Receptor alpha Antikörper (AA 130-339) (ABIN969117)

Target

Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigen
Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reaktivität

  • 468
  • 172
  • 164
  • 18
  • 16
  • 10
  • 7
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Human

Wirt

  • 383
  • 98
  • 1
Maus

Klonalität

  • 358
  • 125
  • 1
Monoklonal

Konjugat

  • 225
  • 31
  • 21
  • 18
  • 15
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert

Applikation

  • 348
  • 162
  • 142
  • 123
  • 94
  • 85
  • 80
  • 53
  • 38
  • 33
  • 22
  • 15
  • 10
  • 7
  • 7
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA

Klon

8H9A10
  • Bindungsspezifität

    • 30
    • 29
    • 28
    • 26
    • 24
    • 21
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 12
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    AA 130-339

    Verwendungszweck

    ESR1 Antibody

    Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of ESR1 (aa130-339) expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Cepollaro, Lauretani, Gozzini, Masi, Falchetti, Del Monte, Carbonell-Sala, Tanini, Corsi, Bandinelli, Ferrucci, Brandi: "Relationship of volumetric bone mineral density and structural parameters with ERalpha gene polymorphisms." in: Calcified tissue international, Vol. 80, Issue 5, pp. 307-15, (2007) (PubMed).

  • Target

    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

    Andere Bezeichnung

    ESR1

    Hintergrund

    ESR1: estrogen receptor 1. This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

    UniProt

    P03372

    Pathways

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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