Cytokeratin 5 Antikörper

Produktnummer ABIN969079

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Cytokeratin 5 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für Cytokeratin 5 Antikörper (ABIN969079)

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 1E1

Produktdetails anti-Cytokeratin 5 Antikörper

Verwendungszweck: Cytokeratin 5 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of Cytokeratin 5 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Cytokeratin 5 Antikörper (ABIN969079)

Wang, Li: "Adenovirus-mediated RNA interference against collagen-specific molecular chaperone 47-KDa heat shock protein suppresses scar formation on mouse wounds." in: Cell biology international, Vol. 32, Issue 5, pp. 484-93, (2008) (PubMed).

Nishizawa, Izawa, Inoko, Hayashi, Nagata, Yokoyama, Usukura, Inagaki: "Identification of trichoplein, a novel keratin filament-binding protein." in: Journal of cell science, Vol. 118, Issue Pt 5, pp. 1081-90, (2005) (PubMed).

Gu, Kim, Ichiki, Park, Nagai, Kitajima: "A usual frameshift and delayed termination codon mutation in keratin 5 causes a novel type of epidermolysis bullosa simplex with migratory circinate erythema." in: The Journal of investigative dermatology, Vol. 121, Issue 3, pp. 482-5, (2003) (PubMed).

Details zu Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Andere Bezeichnung: Cytokeratin 5

Hintergrund: Cytokeratin 5, also known as CK5, KRT5. It is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.

Molekulargewicht: 62.3 kDa

Gen-ID: 3852

UniProt: P13647