CST3 Antikörper

Produktnummer ABIN969070

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CST3 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für CST3 Antikörper (ABIN969070)

Target: CST3 (Cystatin C (CST3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CST3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 5H2

Produktdetails anti-CST3 Antikörper

Verwendungszweck: CST3 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CST3 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-CST3 Antikörper (ABIN969070)

Helisalmi, Väkevä, Hiltunen, Soininen: "Flanking markers of cystatin c (CST3) gene do not show association with Alzheimer's disease." in: Dementia and geriatric cognitive disorders, Vol. 27, Issue 4, pp. 318-21, (2009) (PubMed).

Rehman, Fought, Solomon: "N-acetylcysteine effect on serum creatinine and cystatin C levels in CKD patients." in: Clinical journal of the American Society of Nephrology : CJASN, Vol. 3, Issue 6, pp. 1610-4, (2008) (PubMed).

Details zu CST3

Target: CST3 (Cystatin C (CST3))

Andere Bezeichnung: CST3

Hintergrund: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. (provided by RefSeq)Tissue specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.

Molekulargewicht: 42 kDa

Gen-ID: 1471

UniProt: P01034