CHD3 Antikörper

Produktnummer ABIN969052

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CHD3 in WB, IHC, ELISA, ICC und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus und wurde in 1 Publikation erwähnt.

Kurzübersicht für CHD3 Antikörper (ABIN969052)

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CHD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon: 2G4

Produktdetails anti-CHD3 Antikörper

Verwendungszweck: CHD3 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CHD3 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-CHD3 Antikörper (ABIN969052)

Burd, Kinyamu, Miller, Archer: "UV radiation regulates Mi-2 through protein translation and stability." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, (2008) (PubMed).

Details zu CHD3

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Andere Bezeichnung: CHD3

Hintergrund: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Molekulargewicht: 226 kDa

UniProt: Q12873