Der Maus Monoklonal Anti-CD94-Antikörper wurde für ELISA validiert. Er ist geeignet, CD94 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.
KLRD1
Reaktivität: Human
FACS
Wirt: Maus
Monoclonal
HP-3D9
APC
Applikationshinweise
ELISA: 1/10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Lonigro, Mirabile, Munda, Barchitta, Bottino, Fazzio, Di Cataldo, Agodi, Schilirò: "Association between high expression of natural killer related-genes (NCAM/CD94) and early death during induction in children with acute myeloid leukemia." in: Leukemia, Vol. 22, Issue 9, pp. 1778-81, (2008) (PubMed).
Masilamani, Narayanan, Prieto, Borrego, Coligan: "Uncommon endocytic and trafficking pathway of the natural killer cell CD94/NKG2A inhibitory receptor." in: Traffic (Copenhagen, Denmark), Vol. 9, Issue 6, pp. 1019-34, (2008) (PubMed).
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Tissue specificity: Natural killer cells.