CD37 Antikörper

Produktnummer ABIN969022

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD37 in ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human und Maus und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für CD37 Antikörper (ABIN969022)

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD37 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC)

Klon: 2B8

Produktdetails anti-CD37 Antikörper

Verwendungszweck: CD37 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of CD37 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-CD37 Antikörper (ABIN969022)

Wehkamp, Wang, Kübler, Nuding, Gregorieff, Schnabel, Kays, Fellermann, Burk, Schwab, Clevers, Bevins, Stange: "The Paneth cell alpha-defensin deficiency of ileal Crohn's disease is linked to Wnt/Tcf-4." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 5, pp. 3109-18, (2007) (PubMed).

van Spriel, Puls, Sofi, Pouniotis, Hochrein, Orinska, Knobeloch, Plebanski, Wright: "A regulatory role for CD37 in T cell proliferation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 5, pp. 2953-61, (2004) (PubMed).

Details zu CD37

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Andere Bezeichnung: CD37

Hintergrund: CD37, also known as GP52-40, TSPAN26, MGC120234. Enterz Protein NP_001035120. It is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 31.7 kDa

Gen-ID: 951

UniProt: P11049

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response