CCT2 Antikörper

Produktnummer ABIN969010

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CCT2 in WB, ELISA, ICC und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte und Affe und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für CCT2 Antikörper (ABIN969010)

Target: CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon: 5B5C4

Produktdetails anti-CCT2 Antikörper

Verwendungszweck: CCT2 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CCT2 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-CCT2 Antikörper (ABIN969010)

Abe, Yoon, Kubota, Mendoza, Gygi, Blenis: "p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling." in: The Journal of biological chemistry, Vol. 284, Issue 22, pp. 14939-48, (2009) (PubMed).

Goudreault, DAmbrosio, Kean, Mullin, Larsen, Sanchez, Chaudhry, Chen, Sicheri, Nesvizhskii, Aebersold, Raught, Gingras: "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 1, pp. 157-71, (2009) (PubMed).

Details zu CCT2

Target: CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

Andere Bezeichnung: CCT2

Hintergrund: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 54 kDa

UniProt: P78371