CARM1 Antikörper

Produktnummer ABIN969002

Der Maus Monoklonal Anti-CARM1-Antikörper wurde für WB, ELISA, IHC, FACS und ICC validiert. Er ist geeignet, CARM1 in Proben von Human, Ratte und Affe zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für CARM1 Antikörper (ABIN969002)

Target: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Reaktivität: Human, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CARM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: 3H2

Produktdetails anti-CARM1 Antikörper

Verwendungszweck: CARM1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CARM1 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-CARM1 Antikörper (ABIN969002)

Fauquier, Duboé, Joré, Trouche, Vandel: "Dual role of the arginine methyltransferase CARM1 in the regulation of c-Fos target genes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 9, pp. 3337-47, (2008) (PubMed).

Kleinschmidt, Streubel, Samans, Krause, Bauer: "The protein arginine methyltransferases CARM1 and PRMT1 cooperate in gene regulation." in: Nucleic acids research, Vol. 36, Issue 10, pp. 3202-13, (2008) (PubMed).

Details zu CARM1

Target: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Andere Bezeichnung: CARM1

Hintergrund: Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al. 2002 (PubMed 11724789). Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.

Molekulargewicht: 65 kDa

UniProt: Q86X55

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation