BMP4 Antikörper

Produktnummer ABIN968986

Dieses Maus Monoklonal-Antikörper erkennt spezifisch BMP4 in ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für BMP4 Antikörper (ABIN968986)

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BMP4 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 10F4B4

Produktdetails anti-BMP4 Antikörper

Verwendungszweck: BMP4 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human BMP4 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-BMP4 Antikörper (ABIN968986)

Solmesky, Abekasis, Bulvik, Weil: "Bone morphogenetic protein signaling is involved in human mesenchymal stem cell survival in serum-free medium." in: Stem cells and development, Vol. 18, Issue 9, pp. 1283-92, (2009) (PubMed).

Yerges, Klei, Cauley, Roeder, Kammerer, Moffett, Ensrud, Nestlerode, Marshall, Hoffman, Lewis, Lang, Barrett-Connor, Ferrell, Orwoll, Zmuda: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, (2009) (PubMed).

Details zu BMP4

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Andere Bezeichnung: BMP4

Hintergrund: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors.BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

Molekulargewicht: 64 kDa

Gen-ID: 652

UniProt: P12644

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development