AAT Antikörper

Produktnummer ABIN968939

Produktdetails

Target: AAT

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human AAT expressed in E. coli.

Klon: 2B12

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen

El-Akawi, Al-Hindawi, Bashir: "Alpha-1 antitrypsin (alpha1-AT) plasma levels in lung, prostate and breast cancer patients." in: Neuro endocrinology letters, Vol. 29, Issue 4, pp. 482-4, (2008) (PubMed).

Liu, Qian, Gritsenko, Camp, Monroe, Moore, Smith: "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry." in: Journal of proteome research, Vol. 4, Issue 6, pp. 2070-80, (2005) (PubMed).

Antigendetails

Target: AAT

Synonyme: A1A antikoerper, A1AT antikoerper, AAT antikoerper, PI antikoerper, PI1 antikoerper, PRO2275 antikoerper, alpha1AT antikoerper, serpin family A member 1 antikoerper, SERPINA1 antikoerper

Hintergrund:

Description: AAT, also known as SERPINA1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.

Aliases: PI, A1A, AAT, PI1, A1AT, SERPINA1

Molekulargewicht: 47 kDa

Gen-ID: 5265

HGNC: 5265