Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-AAT Antikörper wird verwendet zum Nachweis von AAT in Proben von Human und Maus. Er wurde validiert für WB und ELISA.
Reaktivität: Human
WB, ELISA, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA: 1/10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
El-Akawi, Al-Hindawi, Bashir: "Alpha-1 antitrypsin (alpha1-AT) plasma levels in lung, prostate and breast cancer patients." in: Neuro endocrinology letters, Vol. 29, Issue 4, pp. 482-4, (2008) (PubMed).
Liu, Qian, Gritsenko, Camp, Monroe, Moore, Smith: "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry." in: Journal of proteome research, Vol. 4, Issue 6, pp. 2070-80, (2005) (PubMed).
Target
AAT
Hintergrund
AAT, also known as SERPINA1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.