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TGOLN2 Antikörper (AA 31-244)

TGOLN2 Reaktivität: Ratte WB, IF Wirt: Maus Monoclonal 2-TGN38 unconjugated
Produktnummer ABIN968238
  • Target Alle TGOLN2 Antikörper anzeigen
    TGOLN2 (Trans-Golgi Network Protein 2 (TGOLN2))
    Bindungsspezifität
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-244
    Reaktivität
    • 40
    • 7
    • 5
    • 2
    • 1
    • 1
    Ratte
    Wirt
    • 36
    • 5
    • 2
    Maus
    Klonalität
    • 29
    • 12
    Monoklonal
    Konjugat
    • 28
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TGOLN2 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 13
    • 11
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Rat TGN38 aa. 31-244
    Klon
    2-TGN38
    Isotyp
    IgG1
    Top Product
    Discover our top product TGOLN2 Primärantikörper
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    Related Products: ABIN968545, ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20° C.
  • Mary, Charrasse, Meriane, Comunale, Travo, Blangy, Gauthier-Rouvière: "Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism." in: Molecular biology of the cell, Vol. 13, Issue 1, pp. 285-301, (2002) (PubMed).

    Ozawa, Kondo, Hori, Kitao, Stern, Eisenmenger, Ogawa, Ohshima: "Expression of the oxygen-regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport." in: The Journal of clinical investigation, Vol. 108, Issue 1, pp. 41-50, (2001) (PubMed).

    Xu, Shen, Joseph, Bryant, Luo, Frankel, Rotunda, Foster: "Mitogenic phospholipase D activity is restricted to caveolin-enriched membrane microdomains." in: Biochemical and biophysical research communications, Vol. 273, Issue 1, pp. 77-83, (2000) (PubMed).

    Humphrey, Peters, Yuan, Bonifacino: "Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence." in: The Journal of cell biology, Vol. 120, Issue 5, pp. 1123-35, (1993) (PubMed).

  • Target
    TGOLN2 (Trans-Golgi Network Protein 2 (TGOLN2))
    Andere Bezeichnung
    TGN38 (TGOLN2 Produkte)
    Synonyme
    TGN38B antikoerper, TGN41 antikoerper, TGN46 antikoerper, Ttgn2 antikoerper, TGN38 antikoerper, TGN48 antikoerper, TGN51 antikoerper, TTGN2 antikoerper, TGOLN2 antikoerper, DKFZp469D101 antikoerper, Tgn38 antikoerper, Tgoln1 antikoerper, Ttgn1 antikoerper, trans-golgi network protein 2 antikoerper, Tgoln2 antikoerper, TGOLN2 antikoerper
    Hintergrund
    Newly synthesized proteins exit the ER and move to the cis-Golgi network (CGN) where they traverse the cis-medial and trans-cisternae before reaching the trans-Golgi network (TGN). N-linked oligosaccharide processing occurs in the TGN, and proteins are sorted to the plasma membrane, lysosomes, endosomes, and secretory granules. TGN38 is a type I integral membrane protein primarily localized to the TGN. It is involved in the sorting of nascent proteins into individual carrier vesicles for transport to appropriate destinations. It is thought to heterodimerize with TGN41 and participate in exocytic budding from the TGN. TGN38 has a molecular weight of 85 to 95 kDa. The core polypeptide represents approximately 38 kDa, while the remainder is accounted for by N- and O-linked oligosaccharide chains. A 286 aa N-terminal lumenal domain, a 21 aa membrane spanning domain, and a 33 aa C-terminal cytoplasmic tail comprise the structure of TGN38. The cytoplasmic tail contains a tyrosine-based motif, YQRL, that is thought to be involved in TGN localization. Therefore, TGN38 mediates the localization of various proteins to the TGN and serves as a TGN retrieval signal. This antibody is routinely tested by western blot analysis.
    Synonyms: Trans Golgi Network-38
    Molekulargewicht
    85-95 kDa
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