Striatin Antikörper (AA 450-600)

Produktnummer ABIN968207

Produktdetails anti-Striatin Antikörper

Target: Striatin (STRN)

Bindungsspezifität: AA 450-600

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Striatin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Kreuzreaktivität: Maus, Human, Hund

Produktmerkmale: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Rat Striatin aa. 450-600

Klon: 6-Striatin

Isotyp: IgG2b

Anwendungsinformationen

Kommentare:

Related Products: ABIN968545, ABIN967389

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store undiluted at -20° C.

Referenzen für anti-Striatin Antikörper (ABIN968207)

Castets, Rakitina, Gaillard, Moqrich, Mattei, Monneron: "Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain." in: The Journal of biological chemistry, Vol. 275, Issue 26, pp. 19970-7, (2000) (PubMed).

Castets, Bartoli, Barnier, Baillat, Salin, Moqrich, Bourgeois, Denizot, Rougon, Calothy, Monneron: "A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons." in: The Journal of cell biology, Vol. 134, Issue 4, pp. 1051-62, (1996) (PubMed).

Details zu Striatin

Target: Striatin (STRN)

Andere Bezeichnung: Striatin (STRN Produkte)

Synonyme: SG2NA antikoerper, AU022939 antikoerper, D130055P19 antikoerper, Xstriatin antikoerper, strn antikoerper, striatin antikoerper, striatin, calmodulin binding protein antikoerper, striatin S homeolog antikoerper, STRN antikoerper, Strn antikoerper, strn.S antikoerper

Hintergrund: Signal transmission between neurons is regulated by the Ca2+-dependent release of neurotransmitters at the synapse. Striatin is a protein identified in the synaptosomal fraction of rat brain. Reports of sequence homology searches have shown that striatin belongs to a family of proteins with the repeated WD motif (the beta-transducin repeat or the WD-40 repeat) found in regulatory proteins. Striatin also binds calmodulin in a Ca2+-dependent manner. Immunolocalization and mRNA expression found striatin in the central nervous system, particularly enriched in neurons of the striatum and motor neurons. Furthermore, subcellular localization studies indicated that Striatin is tightly associated with the plasma membrane. Thus, striatin may play an important role in the Ca2+-dependent events occurring at the synapse.

Molekulargewicht: 110 kDa

Pathways: Nuclear Hormone Receptor Binding, Cell-Cell Junction Organization