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TFCP2 Antikörper (AA 205-414)

TFCP2 Reaktivität: Human, Maus, Ratte, Hund WB, IF Wirt: Maus Monoclonal 14-LSF unconjugated
Produktnummer ABIN968193
  • Target Alle TFCP2 Antikörper anzeigen
    TFCP2 (Transcription Factor CP2 (TFCP2))
    Bindungsspezifität
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 205-414
    Reaktivität
    • 35
    • 21
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund
    Wirt
    • 30
    • 6
    Maus
    Klonalität
    • 33
    • 3
    Monoklonal
    Konjugat
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TFCP2 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 13
    • 10
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Kreuzreaktivität
    Maus, Ratte (Rattus), Hund
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human LSF aa. 205-414
    Klon
    14-LSF
    Isotyp
    IgG1
    Top Product
    Discover our top product TFCP2 Primärantikörper
  • Kommentare

    Related Products: ABIN968551, ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20° C.
  • Volker, Rameh, Zhu, DeCaprio, Hansen: "Mitogenic stimulation of resting T cells causes rapid phosphorylation of the transcription factor LSF and increased DNA-binding activity." in: Genes & development, Vol. 11, Issue 11, pp. 1435-46, (1997) (PubMed).

    Shirra, Zhu, Huang, Pallas, Hansen: "One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs." in: Molecular and cellular biology, Vol. 14, Issue 8, pp. 5076-87, (1994) (PubMed).

  • Target
    TFCP2 (Transcription Factor CP2 (TFCP2))
    Andere Bezeichnung
    LSF (TFCP2 Produkte)
    Synonyme
    cp2 antikoerper, lsf antikoerper, sef antikoerper, lbp-1c antikoerper, tfcp2c antikoerper, MGC75945 antikoerper, TFCP2 antikoerper, lbp1c antikoerper, lsf1d antikoerper, TCFCP2 antikoerper, LBP1C antikoerper, LSF antikoerper, LSF1D antikoerper, SEF antikoerper, TFCP2C antikoerper, CP-2 antikoerper, CP2 antikoerper, D230015P20Rik antikoerper, LBP-1c antikoerper, LBP-1d antikoerper, LBP1 antikoerper, Tcfcp2 antikoerper, UBP-1 antikoerper, transcription factor CP2 antikoerper, transcription factor CP2 L homeolog antikoerper, tfcp2 antikoerper, TFCP2 antikoerper, tfcp2.L antikoerper, Tfcp2 antikoerper
    Hintergrund
    LSF (alphaCP2 or LBP-1c) is a transcription factor originally identified by its binding to, and induction of, the SV40 late promoter. LSF displays some similarity to the Elf-1/NTF transcription factors of Drosophila. It is primarily found in its dimeric form in solution, however it is the tetrameric form that recognizes a center-to-center 10 bp repeat. LSF-1D (LBP-1d) is the product of an alternative splicing event, resulting in a deletion of a 51 amino acid segment that corresponds with the DNA-binding region of LSF. LSF-1D is found in the cytoplasm, not in the nucleus, and can interact with LSF to form a heterotetramer that can interfere with LSF DNA binding. In mitogen-stimulated human peripheral T cells, LSF is phosphorylated on amino acid 291, which increases its DNA binding activity. Thus, LSF-mediated gene transcription is regulated by its phosphorylation and/or its interaction with LSF-1D during cell growth. This antibody is routinely tested by western blot analysis.
    Synonyms: alphaCP2, LBP-1c
    Molekulargewicht
    63 kDa
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