GSTP1 Antikörper (AA 5-210)

Produktnummer ABIN968135

Der Maus Monoklonal Anti-GSTP1-Antikörper wurde für WB, IHC, IP und IF validiert. Er ist geeignet, GSTP1 in Proben von Human, Maus, Ratte und Hund zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für GSTP1 Antikörper (AA 5-210) (ABIN968135)

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GSTP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Klon: 3-GST

Produktdetails anti-GSTP1 Antikörper

Bindungsspezifität: AA 5-210

Kreuzreaktivität: Maus, Ratte (Rattus), Hund

Produktmerkmale: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Human GST-pi aa. 5-210

Isotyp: IgG1

Anwendungsinformationen

Kommentare:

Related Products: ABIN967389, ABIN968535

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store undiluted at -20° C.

Referenzen für anti-GSTP1 Antikörper (ABIN968135)

Ali-Osman, Akande, Antoun, Mao, Buolamwini: "Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins." in: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10004-12, (1997) (PubMed).

Zhou, Evans, London, Xia, Zou, Shen, Clapper: "Glutathione S-transferase expression in hepatitis B virus-associated human hepatocellular carcinogenesis." in: Cancer research, Vol. 57, Issue 13, pp. 2749-53, (1997) (PubMed).

Kano, Sakai, Muramatsu: "Structure and expression of a human class pi glutathione S-transferase messenger RNA." in: Cancer research, Vol. 47, Issue 21, pp. 5626-30, (1987) (PubMed).

Details zu GSTP1

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Andere Bezeichnung: GST-pi

Hintergrund: Glutathione-S-Transferases (GSTs) are a family of dimeric proteins that catalyze the S-conjugation of glutathione with many compounds for detoxification. The GSTs are categorized into four classes based on their biochemical and structural properties: alpha, µ, pi, and theta. GST-pi is of particular interest because it is over-expressed in many tumors, but is either absent or expressed at low levels in the corresponding normal tissues. This high expression of GST-pi is associated with malignant transformation and correlates with a decrease in GST activity. Three different GST-pi proteins have been isolated and designated as hGSTP1A, hGSTP1B, and hGSTP1C. These isoforms are nearly identical, varying by only one to two amino acids. This antibody is routinely tested by western blot analysis.
Synonyms: Glutathione-S-Transferase-pi

Molekulargewicht: 23 kDa

Pathways: Cellular Response to Molecule of Bacterial Origin