Annexin VII Antikörper (AA 34-159)

Produktnummer ABIN968099

Es sind 5+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-Annexin VII Antikörper wird verwendet zum Nachweis von Annexin VII in Proben von Human. Er wurde validiert für WB, IHC, IF und IP.

Kurzübersicht für Annexin VII Antikörper (AA 34-159) (ABIN968099)

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Annexin VII Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: 5-Annexin VII

Produktdetails anti-Annexin VII Antikörper

Bindungsspezifität: AA 34-159

Produktmerkmale: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Human Annexin VII aa. 34-159

Isotyp: IgG1

Anwendungsinformationen

Kommentare:

Related Products: ABIN968536, ABIN967389

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store undiluted at -20° C.

Referenzen für anti-Annexin VII Antikörper (ABIN968099)

Salzer, Hinterdorfer, Hunger, Borken, Prohaska: "Ca(++)-dependent vesicle release from erythrocytes involves stomatin-specific lipid rafts, synexin (annexin VII), and sorcin." in: Blood, Vol. 99, Issue 7, pp. 2569-77, (2002) (PubMed).

Srivastava, Bubendorf, Srikantan, Fossom, Nolan, Glasman, Leighton, Fehrle, Pittaluga, Raffeld, Koivisto, Willi, Gasser, Kononen, Sauter, Kallioniemi, Srivastava, Pollard: "ANX7, a candidate tumor suppressor gene for prostate cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 8, pp. 4575-80, (2001) (PubMed).

Furge, Chen, Cohen: "Annexin VII and annexin XI are tyrosine phosphorylated in peroxovanadate-treated dogs and in platelet-derived growth factor-treated rat vascular smooth muscle cells." in: The Journal of biological chemistry, Vol. 274, Issue 47, pp. 33504-9, (1999) (PubMed).

Selbert, Fischer, Pongratz, Stewart, Noegel: "Expression and localization of annexin VII (synexin) in muscle cells." in: Journal of cell science, Vol. 108 ( Pt 1), pp. 85-95, (1995) (PubMed).

Magendzo, Shirvan, Cultraro, Srivastava, Pollard, Burns: "Alternative splicing of human synexin mRNA in brain, cardiac, and skeletal muscle alters the unique N-terminal domain." in: The Journal of biological chemistry, Vol. 266, Issue 5, pp. 3228-32, (1991) (PubMed).

Details zu Annexin VII

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Andere Bezeichnung: Annexin VII

Hintergrund: Annexin VII, also known as synexin, is a member of the Annexin family characterized by Ca2+ dependent phospholipid binding. Annexins have a four-fold internal repeat of about 70 amino acids that contains the Ca2+-binding sites. They also have a regulatory NH2-terminal region of 30-40 amino acids. Annexin VII mRNA has been detected in many tissues and is most abundant in brain, heart, skeletal muscle, and lung. Annexin VII mRNA exhibits a tissue dependent polymorphism due to alternative splicing which results in two different isoforms of 47 kDa and 51 kDa. In vitro, Annexin VII aggregates chromaffin granules and enhances membrane fusion in a Ca2+ and GTP-dependent manner. Although the physiological role of Annexin VII is not completely understood, it is believed to influence and regulate Ca2+ dependent events such as secretion at the plasma membrane.
Synonyms: Synexin

Molekulargewicht: 51 kDa