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Syntaxin 6 Antikörper (AA 6-136)

STX6 Reaktivität: Human, Maus, Ratte, Huhn, Hund, Frosch WB, IHC, IF, IP Wirt: Maus Monoclonal 30-Syntaxin 6 unconjugated
Produktnummer ABIN968079
  • Target Alle Syntaxin 6 (STX6) Antikörper anzeigen
    Syntaxin 6 (STX6)
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 6-136
    Reaktivität
    • 63
    • 19
    • 18
    • 11
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Huhn, Hund, Frosch
    Wirt
    • 62
    • 7
    • 3
    • 2
    Maus
    Klonalität
    • 67
    • 7
    Monoklonal
    Konjugat
    • 28
    • 8
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Syntaxin 6 Antikörper ist unkonjugiert
    Applikation
    • 53
    • 34
    • 13
    • 13
    • 9
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Kreuzreaktivität
    Human, Maus, Hund, Huhn, Frosch
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Rat Syntaxin 6 aa. 6-136
    Klon
    30-Syntaxin 6
    Isotyp
    IgG1
    Top Product
    Discover our top product STX6 Primärantikörper
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    Related Products: ABIN968533, ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20°C.
  • Shewan, van Dam, Martin, Luen, Hong, Bryant, James: "GLUT4 recycles via a trans-Golgi network (TGN) subdomain enriched in Syntaxins 6 and 16 but not TGN38: involvement of an acidic targeting motif." in: Molecular biology of the cell, Vol. 14, Issue 3, pp. 973-86, (2003) (PubMed).

    Ramalho-Santos, Moreno, Sutovsky, Chan, Hewitson, Wessel, Simerly, Schatten: "SNAREs in mammalian sperm: possible implications for fertilization." in: Developmental biology, Vol. 223, Issue 1, pp. 54-69, (2000) (PubMed).

  • Target
    Syntaxin 6 (STX6)
    Andere Bezeichnung
    Syntaxin 6 (STX6 Produkte)
    Synonyme
    CG7736 antikoerper, CT23545 antikoerper, Dm Syx6 antikoerper, DmSyx6 antikoerper, Dmel\\CG7736 antikoerper, SYN6 antikoerper, SYX6/10 antikoerper, Syx antikoerper, MGC78971 antikoerper, MGC132090 antikoerper, STX6 antikoerper, fb51b08 antikoerper, wu:fb51b08 antikoerper, zgc:110658 antikoerper, si:dkey-121a11.2 antikoerper, LOC734102 antikoerper, Syx6 antikoerper, Bmsyx6 antikoerper, Syntaxin-6 antikoerper, 2310039E05Rik antikoerper, 2410005I16Rik antikoerper, AA437559 antikoerper, AI415714 antikoerper, AI845861 antikoerper, Syntaxin 6 antikoerper, syntaxin 6 L homeolog antikoerper, syntaxin 6 antikoerper, Syx6 antikoerper, stx6.L antikoerper, STX6 antikoerper, stx6 antikoerper, Stx6 antikoerper
    Hintergrund
    Signal transmission between cells is often regulated by the secretion of neurotransmitters or hormones into the extracellular space. This process is controlled by a complex pathway of membrane trafficking which leads to membrane fusion and secretion. Syntaxin 1 is involved in three important complexes that modulate the secretion process: syntaxin and n-sec-1, syntaxin, VAMP, and SNAP-25, and syntaxin, VAMP, SNAP-25, alphaSNAP, and NSF (20S complex). Syntaxin 6 is a 255 amino acid member of the syntaxin family. It contains a C-terminal transmembrane domain and is located at the Golgi apparatus. In addition, Syntaxin 6 displays significant (47% identity) homology with SNAP-25. In vitro, Syntaxin 6 has been reported to interact with alpha-SNAP. Syntaxin 6 has been reported to have a calculated molecular weight of 30.6 kDa, but has been observed to migrate in a range inbetween ~ 31-35 kDa.
    Molekulargewicht
    31-35 kDa
    Pathways
    Synaptic Vesicle Exocytosis
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