ANXA6 Antikörper (AA 1-673)

Produktnummer ABIN967890

Zitiert in 5+ Publikationen. Der Maus Monoklonal anti-ANXA6 Antikörper (Klon 73-Annexin VI) (ABIN967890) detektiert spezifisch ANXA6 in WB, IHC, IF und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Ratte.

Kurzübersicht für ANXA6 Antikörper (AA 1-673) (ABIN967890)

Target: ANXA6 (Annexin A6 (ANXA6))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ANXA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: 73-Annexin VI

Produktdetails anti-ANXA6 Antikörper

Bindungsspezifität: AA 1-673

Kreuzreaktivität: Ratte (Rattus)

Produktmerkmale: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Human Annexin VI aa. 1-673

Isotyp: IgG1

Anwendungsinformationen

Kommentare:

Related Products: ABIN968537, ABIN967389

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store undiluted at -20°C.

Referenzen für anti-ANXA6 Antikörper (ABIN967890)

Chen, Coustan-Smith, Suzuki, Neale, Mihara, Pui, Campana: "Identification of novel markers for monitoring minimal residual disease in acute lymphoblastic leukemia." in: Blood, Vol. 97, Issue 7, pp. 2115-20, (2001) (PubMed).

Babiychuk, Draeger: "Annexins in cell membrane dynamics. Ca(2+)-regulated association of lipid microdomains." in: The Journal of cell biology, Vol. 150, Issue 5, pp. 1113-24, (2000) (PubMed).

Babiychuk, Palstra, Schaller, Kämpfer, Draeger: "Annexin VI participates in the formation of a reversible, membrane-cytoskeleton complex in smooth muscle cells." in: The Journal of biological chemistry, Vol. 274, Issue 49, pp. 35191-5, (2000) (PubMed).

Yu, Cassara, Weller: "Phosphatidylinositide 3-kinase localizes to cytoplasmic lipid bodies in human polymorphonuclear leukocytes and other myeloid-derived cells." in: Blood, Vol. 95, Issue 3, pp. 1078-85, (2000) (PubMed).

Crompton, Moss, Crumpton: "Diversity in the lipocortin/calpactin family." in: Cell, Vol. 55, Issue 1, pp. 1-3, (1988) (PubMed).

Details zu ANXA6

Target: ANXA6 (Annexin A6 (ANXA6))

Andere Bezeichnung: Annexin VI

Hintergrund: Annexins are a widely expressed family of Ca[2+] and phospholipid-binding proteins. At least ten have been identified in mammalian tissues. They have also been identified in Drosophila, Hydra, and Dictyostelium. Annexin VI is a 70 kDa member of the annexin family. While most of the other annexin family members have a four amino acid sequence repeat, Annexin VI displays an eight residue repeat. It is a widely expressed protein, found in lymphocytes, neurons, and many other cell types. Work on annexins has addressed the possible role of Annexin VI in various stages of the endocytic pathway. Some studies suggest that Annexin VI is required for coated-vesicle budding. However, other research directly contradicts this data. Thus, the role of Annexin VI is still under investigation.

Molekulargewicht: 70 kDa