JUP Antikörper (AA 553-738)

Produktnummer ABIN967859

Es sind 5+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-JUP Antikörper wird verwendet zum Nachweis von JUP in Proben von Human, Maus, Ratte, Huhn und Hund. Er wurde validiert für WB, IF, IHC und IP.

Kurzübersicht für JUP Antikörper (AA 553-738) (ABIN967859)

Target: JUP (Junction Plakoglobin (JUP))

Reaktivität: Human, Maus, Ratte, Huhn, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser JUP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Klon: 15-gamma

Produktdetails anti-JUP Antikörper

Bindungsspezifität: AA 553-738

Kreuzreaktivität: Huhn, Hund, Maus, Ratte (Rattus)

Produktmerkmale: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Human gamma-Catenin aa. 553-738

Isotyp: IgG2a

Anwendungsinformationen

Kommentare:

Related Products: ABIN968535, ABIN967389

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store undiluted at -20° C.

Referenzen für anti-JUP Antikörper (ABIN967859)

Mary, Charrasse, Meriane, Comunale, Travo, Blangy, Gauthier-Rouvière: "Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism." in: Molecular biology of the cell, Vol. 13, Issue 1, pp. 285-301, (2002) (PubMed).

Merritt, Berika, Zhai, Kirk, Ji, Hardman, Garrod: "Suprabasal desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5846-58, (2002) (PubMed).

Peng, Mandai, Nakanishi, Ikeda, Asada, Momose, Shibamoto, Yanagihara, Shiozaki, Monden, Takeichi, Takai: "Restoration of E-cadherin-based cell-cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line." in: Oncogene, Vol. 21, Issue 26, pp. 4108-19, (2002) (PubMed).

Müller, Choidas, Reichmann, Ullrich: "Phosphorylation and free pool of beta-catenin are regulated by tyrosine kinases and tyrosine phosphatases during epithelial cell migration." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10173-83, (1999) (PubMed).

McCrea, Turck, Gumbiner: "A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin." in: Science (New York, N.Y.), Vol. 254, Issue 5036, pp. 1359-61, (1992) (PubMed).

Details zu JUP

Target: JUP (Junction Plakoglobin (JUP))

Andere Bezeichnung: gamma-Catenin

Molekulargewicht: 82 kDa

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location