SOX17 Antikörper

Produktnummer ABIN967681

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SOX17 in WB, IF, BI und ICS. Er zeigt eine Reaktivität gegenüber Human und wurde in 6+ Publikationen erwähnt.

Kurzübersicht für SOX17 Antikörper (ABIN967681)

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SOX17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), BioImaging (BI), Intracellular Staining (ICS)

Klon: P7-969

Produktdetails anti-SOX17 Antikörper

Marke: BD Pharmingen™

Produktmerkmale: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. An isotype control should be used at the same concentration as the antibody of interest.
3. Please refer to us for technical protocols.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
5. Sodium azide is a reversible inhibitor of oxidative metabolism, therefore, antibody preparations containing this preservative agent must not be used in cell cultures nor injected into animals. Sodium azide may be removed by washing stained cells or plate-bound antibody or dialyzing soluble antibody in sodium azide-free buffer. Since endotoxin may also affect the results of functional studies, we recommend the NA/LE (No Azide/Low Endotoxin) antibody format, if available, for in vitro and in vivo use.
6. Triton is a trademark of the Dow Chemical Company.

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Human Sox17 Recombinant Protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Kommentare:

Related Products: ABIN967389

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-SOX17 Antikörper (ABIN967681)

Serrano, Gandillet, Pearson, Lacaud, Kouskoff: "Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification." in: Blood, Vol. 115, Issue 19, pp. 3895-8, (2010) (PubMed).

Séguin, Draper, Nagy, Rossant: "Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells." in: Cell stem cell, Vol. 3, Issue 2, pp. 182-95, (2008) (PubMed).

Kim, Saunders, Morrison: "Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells." in: Cell, Vol. 130, Issue 3, pp. 470-83, (2007) (PubMed).

DAmour, Agulnick, Eliazer, Kelly, Kroon, Baetge: "Efficient differentiation of human embryonic stem cells to definitive endoderm." in: Nature biotechnology, Vol. 23, Issue 12, pp. 1534-41, (2005) (PubMed).

Collet, Secombes: "Construction and analysis of a secreting expression vector for fish cells." in: Vaccine, Vol. 23, Issue 13, pp. 1534-9, (2005) (PubMed).

Katoh: "Molecular cloning and characterization of human SOX17." in: International journal of molecular medicine, Vol. 9, Issue 2, pp. 153-7, (2002) (PubMed).

Details zu SOX17

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Andere Bezeichnung: SOX17

Hintergrund: The P7-969 monoclonal antibody reacts with human Sox17, a member of the SOX (SRY-releated HMG-box) family of transcription factors. SOX family members contain a DNA binding domain (HMG-box) and are involved in the control of development. Sox17 is expressed in primitive and definitive endoderm and regulates fetal and neonatal hematopoietic stem cell proliferation.
Synonyms: SOX-17, SOX17, FLJ22252

Molekulargewicht: 45 kDa

Gen-ID: 64321