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SNCA Antikörper

SNCA Reaktivität: Human WB, ELISA, IHC Monoclonal unconjugated
Produktnummer ABIN967061
  • Target Alle SNCA Antikörper anzeigen
    SNCA (Synuclein, alpha (SNCA))
    Reaktivität
    • 294
    • 201
    • 201
    • 14
    • 10
    • 10
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    Bitte anfragen
    Klonalität
    • 223
    • 122
    Monoklonal
    Konjugat
    • 146
    • 25
    • 22
    • 17
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    Dieser SNCA Antikörper ist unkonjugiert
    Applikation
    • 240
    • 164
    • 111
    • 80
    • 77
    • 68
    • 68
    • 52
    • 48
    • 44
    • 23
    • 21
    • 10
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    Ni-NTA purified truncated recombinant SNCA expressed in E. Coli strain BL21 (DE3)
    Aufreinigung
    Crude ascites.
    Top Product
    Discover our top product SNCA Primärantikörper
  • Applikationshinweise
    Western Blot: 1: 500- 1: 2,000
    IHC(P): 1: 500- 1: 2,000
    IHC(F): 1: 500- 1: 2,000
    ELISA: Propose dilution 1: 10,000
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Lagerung
    -20 °C
  • Target
    SNCA (Synuclein, alpha (SNCA))
    Andere Bezeichnung
    SNCA (SNCA Produkte)
    Synonyme
    snca antikoerper, MGC64356 antikoerper, LOC619283 antikoerper, NACP antikoerper, alphaSYN antikoerper, PARK1 antikoerper, PARK4 antikoerper, PD1 antikoerper, synuclein alpha L homeolog antikoerper, alpha-synuclein antikoerper, synuclein alpha antikoerper, synuclein, alpha antikoerper, snca.L antikoerper, LOC619283 antikoerper, SNCA antikoerper, Snca antikoerper
    Hintergrund
    Alpha-synuclein (SNCA), with 140-amino acid protein (about 15kDa), belongs to the synuclein family, which also includes beta- and gamma-synuclein. SNCA is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). SNCA is implicated in the regulation of dopamine release and transport. The triplication of the SNCA can cause Parkinson disease (PD) and diffuse Lewy body disease within the same kindred. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Immunohistochemistry for SNCA has become the histological technique of choice for the diagnosis for Parkinson's disease, Dementia with Lewy bodies and Multiple System Atrophy.
    Gen-ID
    6622
    Pathways
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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