SCD Antikörper

Produktnummer ABIN966997

Dieses Monoklonal-Antikörper erkennt spezifisch SCD in WB, ELISA, IHC und IP. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für SCD Antikörper (ABIN966997)

Target: SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

Reaktivität: Human, Maus

Wirt: Bitte anfragen

Klonalität: Monoklonal

Konjugat: Dieser SCD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-SCD Antikörper

Spezifität: Full length recombinant protein. Reacts with human and mouse proteins.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Western blot, ELISA, IP, and IHC in obesity research.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1mg/ml

Buffer: PBS, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu SCD

Target: SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

Andere Bezeichnung: SCD1

Hintergrund: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The SCD1 gene is tightly regulated by signals such as insulin, leptin, carbohydrate, fatty acids and temperature. The enzyme (mouse 355aa, rat 358aa, ~37 KDa) is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. The SCD-1 expression is higher in female than male mouse. The repression of RNA levels and enzyme activity of hepatic SCD-1 by Leptin has been shown to significantly reduce the triglyceride storage, VLDL production and therefore an increase in fatty acid oxidation. Inhibition of SCD-1 could be of benefit for treatment of obesity, hepatic steatosis and other metabolic disorders.

Gen-ID: 20249

Pathways: Brown Fat Cell Differentiation