Reticulon 3 Antikörper (RTN3)

Details for Product anti-RTN3 Antibody No. ABIN966979
Antigen
  • ASYIP
  • HAP
  • NSPL2
  • NSPLII
  • RTN3-A1
  • MGC56439
  • zgc:56439
  • zgc:77630
  • RTN3
  • hap
  • asyip
  • nspl2
  • xrtn3
  • nsplii
  • rtn3-a1
  • RTN3w
  • rtn3
  • XRTN3
  • rtn3-a
  • rtn3-b
  • reticulon 3
  • reticulon 3 L homeolog
  • reticulon-3
  • reticulon 3 S homeolog
  • RTN3
  • Rtn3
  • rtn3
  • rnt3
  • rtn3.L
  • LOC107131155
  • rtn3.S
Reaktivität
Human
36
10
10
1
1
1
1
Wirt
Maus
20
16
Klonalität (Klon)
Monoklonal ()
Applikation
ELISA, Western Blotting (WB)
23
18
17
9
4
2
1
1
1
1
1
Optionen
Immunogen Purified recombinant fragment of RTN3 expressed in E. Coli.
Klon 1E11
Isotyp IgG2a
Reinigung Ascitic fluid
Plasmids, Primers & others Plasmide, Primers & weitere Reticulon 3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung RTN3 (RTN3 Antibody Abstract)
Hintergrund RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
Synonyms: HAP, ASYIP, NSPL2, NSPLII, RTN3-A1
Molekulargewicht 113kDa
Gen-ID 10313
Applikations-hinweise Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Produkt verwendet in: Wakana, Koyama, Nakajima, Hatsuzawa, Nagahama, Tani, Hauri, Melançon, Tagaya: "Reticulon 3 is involved in membrane trafficking between the endoplasmic reticulum and Golgi." in: Biochemical and biophysical research communications, Vol. 334, Issue 4, pp. 1198-205, 2005 (PubMed).

Brain, Wilson, Johnson, Sanderson, Bestari, Hanson, Sibley, Solomon: "Effects of a mixture of tetracyclines to Lemna gibba and Myriophyllum sibiricum evaluated in aquatic microcosms." in: Environmental pollution (Barking, Essex : 1987), Vol. 138, Issue 3, pp. 425-42, 2005 (PubMed).

Cai, Saiyin, Lin, Zhang, Tang, Pan, Yu: "Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain." in: Brain research. Molecular brain research, Vol. 138, Issue 2, pp. 236-43, 2005 (PubMed).

Oertle, Klinger, Stuermer, Schwab: "A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 10, pp. 1238-47, 2003 (PubMed).

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