PTK6 Antikörper

Produktnummer ABIN966923

Der Monoklonal Anti-PTK6-Antikörper wurde für ELISA validiert. Er ist geeignet, PTK6 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für PTK6 Antikörper (ABIN966923)

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Monoklonal

Konjugat: Dieser PTK6 Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-PTK6 Antikörper

Spezifität: Ni-NTA purified truncated recombinant PTK6 expressed in E. Coli strain BL21 (DE3).

Aufreinigung: Antibodies are purified by protein A affinity chromatography

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Referenzen für anti-PTK6 Antikörper (ABIN966923)

Park, Lee, Lee: "Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG." in: Journal of biochemistry, Vol. 119, Issue 2, pp. 235-9, (1997) (PubMed).

Details zu PTK6

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Andere Bezeichnung: PTK6

Hintergrund: PTK6 (protein tyrosine kinase 6, BRK or FLJ42088),with 451-amino acid protein (about 51kDa), encods a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphory-lation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. And Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.

Gen-ID: 5753