POLRMT Antikörper (C-Term)

Produktnummer ABIN966880

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch POLRMT in IHC. Er zeigt eine Reaktivität gegenüber Human und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für POLRMT Antikörper (C-Term) (ABIN966880)

Target: POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLRMT Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-POLRMT Antikörper

Bindungsspezifität: C-Term

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human POLRMT(DNA-directed RNA polymerase, mitochondrial)

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Referenzen für anti-POLRMT Antikörper (ABIN966880)

Bogenhagen, Rousseau, Burke: "The layered structure of human mitochondrial DNA nucleoids." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3665-75, (2008) (PubMed).

Kravchenko, Rogozin, Koonin, Chumakov: "Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin." in: Nature, Vol. 436, Issue 7051, pp. 735-9, (2005) (PubMed).

Gaspari, Falkenberg, Larsson, Gustafsson: "The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells." in: The EMBO journal, Vol. 23, Issue 23, pp. 4606-14, (2004) (PubMed).

Tiranti, Savoia, Forti, DApolito, Centra, Rocchi, Zeviani: "Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database." in: Human molecular genetics, Vol. 6, Issue 4, pp. 615-25, (1997) (PubMed).

Details zu POLRMT

Target: POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))

Andere Bezeichnung: POLRMT

Hintergrund: POLRMT(DNA-directed RNA polymerase, mitochondrial) is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNAdirected RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. POLRMT(DNA-directed RNA polymerase, mitochondrial) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLRMT interacts with TFB1M and TFB2M, leading to the stimulation of family.