Laminin Antikörper

Produktnummer ABIN966476

Produktdetails anti-Laminin Antikörper

Target: Laminin (LN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Laminin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Katze, Schwein

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Immunogen: Human laminin.

Klon: Lam-26

Isotyp: IgG1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 1.2 % sodium acetate or neutral PBS. If 1 mL of PBS is used, the antibody concentration will be 100 µg/mL.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.

Referenzen für anti-Laminin Antikörper (ABIN966476)

Zhang, Vuolteenaho, Tryggvason: "Structure of the human laminin alpha2-chain gene (LAMA2), which is affected in congenital muscular dystrophy." in: The Journal of biological chemistry, Vol. 271, Issue 44, pp. 27664-9, (1996) (PubMed).

Arahata, Hayashi, Mizuno, Yoshida, Ozawa: "Dystrophin-associated glycoprotein and dystrophin co-localisation at sarcolemma in Fukuyama congenital muscular dystrophy." in: Lancet (London, England), Vol. 342, Issue 8871, pp. 623-4, (1993) (PubMed).

Ehrig, Leivo, Argraves, Ruoslahti, Engvall: "Merosin, a tissue-specific basement membrane protein, is a laminin-like protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 9, pp. 3264-8, (1990) (PubMed).

Details zu Laminin

Target: Laminin (LN)

Andere Bezeichnung: Laminin (LN Produkte)

Hintergrund: Laminin is a heterotrimeric extracellular matrix protein consisting of 3 chains: alpha-1,beta-1 and gamma-1, formerly called beta-2 (LAMA2). This gene is over 260, 000 base pairs and contains 64 exons. Laminin is similar with merosin, a basement membrane-associated protein found in placenta, striated muscle, and peripheral nerve, and both of them are members of the same family of basement membrane proteins. And merosin is the same as laminin M, a striated muscle-specific, basal-lamina-associated protein, it may play a primary role in the pathogenesis of that disorder.

Gen-ID: 284217, 16772, 316758

UniProt: P02469, P15800, Q61292, D3ZQN7, P07942, Q60675, P19137, P55268, D4A409, P25391, F1M614, P24043