Insulin Receptor Substrate 1 (IRS1) Antikörper

Details zu Produkt Nr. ABIN966417
Antigen
Reaktivität
Human, Maus, Ratte (Rattus)
622
458
431
32
15
4
4
2
2
1
1
Wirt
Kaninchen
627
20
Klonalität
Polyklonal
Konjugat
Unkonjugiert
23
20
20
20
20
20
20
12
11
10
10
10
10
10
4
2
1
1
1
Applikation
Immunohistochemistry (IHC)
370
239
198
134
130
110
28
25
18
13
12
5
3
3
1
Optionen
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 307.
Spezifität IRS-1 (Ab-307) antibody detects endogenous levels of total IRS-1 protein.
Reinigung The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Antigen
Andere Bezeichnung IRS-1 (IRS1 Antibody Abstract)
Pathways Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Applikations-hinweise IHC: 1:50-1:100.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Produkt verwendet in: Tuncman, Hirosumi, Solinas, Chang, Karin, Hotamisligil: "Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 28, pp. 10741-6, 2006 (PubMed).

Shoelson, Lee, Goldfine: "Inflammation and insulin resistance." in: The Journal of clinical investigation, Vol. 116, Issue 7, pp. 1793-801, 2006 (PubMed).

Steppan, Wang, Whiteman, Birnbaum, Lazar: "Activation of SOCS-3 by resistin." in: Molecular and cellular biology, Vol. 25, Issue 4, pp. 1569-75, 2005 (PubMed).

Frolov, Drozdova, Kazanskaia, Ramdavon: "[The synchronization and desynchronization of the" in: Biulleten' eksperimental'noĭ biologii i meditsiny, Vol. 116, Issue 7, pp. 17-9, 1993 (PubMed).