HHEX Antikörper (N-Term)

Produktnummer ABIN966283

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HHEX in WB. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für HHEX Antikörper (N-Term) (ABIN966283)

Target: HHEX (Hematopoietically Expressed Homeobox (HHEX))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HHEX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HHEX Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Hematopoietically-expressed homeobox protein HHEX(HHEX) detection. Tested with WB in Human, Mouse, Rat.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human HHEX, different from the related mouse sequence by one amino acid.< br/>Immunogen was affinity purified.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.

Referenzen für anti-HHEX Antikörper (ABIN966283)

DElia, Tell, Russo, Arturi, Puglisi, Manfioletti, Gattei, Mack, Cataldi, Filetti, Di Loreto, Damante: "Expression and localization of the homeodomain-containing protein HEX in human thyroid tumors." in: The Journal of clinical endocrinology and metabolism, Vol. 87, Issue 3, pp. 1376-83, (2002) (PubMed).

Hromas, Radich, Collins: "PCR cloning of an orphan homeobox gene (PRH) preferentially expressed in myeloid and liver cells." in: Biochemical and biophysical research communications, Vol. 195, Issue 2, pp. 976-83, (1993) (PubMed).

Details zu HHEX

Target: HHEX (Hematopoietically Expressed Homeobox (HHEX))

Andere Bezeichnung: Hematopoietically-expressed homeobox protein Hhex(Homeobox protein HEX)

Hintergrund: Hematopoietically-expressed homeobox protein HHEX is a protein that in humans is encoded by the HHEX gene. Homeobox genes are members of a family of transcription factors that regulate tissue development in many different organisms. Hromas et al. (1993) set out to identify homeobox genes that might play a role in hematopoiesis. And using somatic cell hybrid analysis, they mapped the HHEX gene to chromosome 10, where the HOX11 gene is located. Homeobox genes are involved in neoplastic transformation of both epithelial and hemopoietic tissues. The divergent homeobox gene HEX is expressed in the anterior visceral endoderm during early mouse development and in some adult tissues of endodermal origin, including liver and thyroid. D'Elia et al. ﾒs findings suggested that regulation of HEX entry in the nucleus of thyrocytes may represent a critical step during human thyroid tumorigenesis.