HAND1 Antikörper (AA 90-190)

Produktnummer ABIN966248

Es gibt 1 Publikation für dieses Produkt. Der Maus Monoklonal anti-HAND1 Antikörper wird verwendet zum Nachweis von HAND1 in Proben von Human. Er wurde validiert für ELISA und WB.

Kurzübersicht für HAND1 Antikörper (AA 90-190) (ABIN966248)

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HAND1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Klon: 8E7A11-8C2F4

Produktdetails anti-HAND1 Antikörper

Bindungsspezifität: AA 90-190

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of HAND1 (aa90-190) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-HAND1 Antikörper (ABIN966248)

Firulli, Howard, McDaid, McIlreavey, Dionne, Centonze, Cserjesi, Virshup, Firulli: "PKA, PKC, and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation." in: Molecular cell, Vol. 12, Issue 5, pp. 1225-37, (2003) (PubMed).

Details zu HAND1

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Andere Bezeichnung: HAND1

Hintergrund: HAND1: heart and neural crest derivatives expressed 1. The protein encoded by this gene belongs to the basic helixloop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
Synonyms: Hxt, eHand, Thing1, bHLHa27

Gen-ID: 9421

Pathways: Tube Formation