Estrogen Receptor alpha Antikörper

Produktnummer ABIN966104

Produktdetails anti-Estrogen Receptor alpha Antikörper

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Spezifität: Estrogen Receptor- (Ab-118) antibody detects endogenous levels of total Estrogen Receptor- protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human Estrogen Receptor- around the phosphorylation site of serine118 (Q-L-SP-P-F).

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000
IHC: 1:50~1:100.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-Estrogen Receptor alpha Antikörper (ABIN966104)

Pentecost, Bradley, Gierthy, Ding, Fasco: "Gene regulation in an MCF-7 cell line that naturally expresses an estrogen receptor unable to directly bind DNA." in: Molecular and cellular endocrinology, Vol. 238, Issue 1-2, pp. 9-25, (2005) (PubMed).

Medunjanin, Hermani, De Servi, Grisouard, Rincke, Mayer: "Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity." in: The Journal of biological chemistry, Vol. 280, Issue 38, pp. 33006-14, (2005) (PubMed).

Masuhiro, Mezaki, Sakari, Takeyama, Yoshida, Inoue, Yanagisawa, Hanazawa, Omalley, Kato: "Splicing potentiation by growth factor signals via estrogen receptor phosphorylation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 23, pp. 8126-31, (2005) (PubMed).

Details zu Estrogen Receptor alpha

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Andere Bezeichnung: Estrogen Receptor-alpha (ESR1 Produkte)

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly