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Estrogen Receptor alpha Antikörper

Der Kaninchen Polyklonal Anti-Estrogen Receptor alpha-Antikörper wurde für IHC validiert. Er ist geeignet, Estrogen Receptor alpha in Proben von Human und Maus zu detektieren. Es sind 3+ Publikationen verfügbar.
Produktnummer ABIN966104

Kurzübersicht für Estrogen Receptor alpha Antikörper (ABIN966104)

Target

Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigen
Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reaktivität

  • 469
  • 172
  • 164
  • 18
  • 16
  • 10
  • 7
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Human, Maus

Wirt

  • 383
  • 99
  • 1
Kaninchen

Klonalität

  • 358
  • 126
  • 1
Polyklonal

Konjugat

  • 226
  • 31
  • 21
  • 18
  • 15
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert

Applikation

  • 348
  • 163
  • 142
  • 123
  • 94
  • 85
  • 80
  • 53
  • 38
  • 33
  • 22
  • 15
  • 10
  • 7
  • 7
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)
  • Spezifität

    Estrogen Receptor- (Ab-118) antibody detects endogenous levels of total Estrogen Receptor- protein.

    Aufreinigung

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    Immunogen

    The antiserum was produced against synthesized non-phosphopeptide derived from human Estrogen Receptor- around the phosphorylation site of serine118 (Q-L-SP-P-F).
  • Applikationshinweise

    WB: 1:500~1:1000
    IHC: 1:50~1:100.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    100ug/100ul.

    Buffer

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C
  • Pentecost, Bradley, Gierthy, Ding, Fasco: "Gene regulation in an MCF-7 cell line that naturally expresses an estrogen receptor unable to directly bind DNA." in: Molecular and cellular endocrinology, Vol. 238, Issue 1-2, pp. 9-25, (2005) (PubMed).

    Medunjanin, Hermani, De Servi, Grisouard, Rincke, Mayer: "Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity." in: The Journal of biological chemistry, Vol. 280, Issue 38, pp. 33006-14, (2005) (PubMed).

    Masuhiro, Mezaki, Sakari, Takeyama, Yoshida, Inoue, Yanagisawa, Hanazawa, Omalley, Kato: "Splicing potentiation by growth factor signals via estrogen receptor phosphorylation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 23, pp. 8126-31, (2005) (PubMed).

  • Target

    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

    Andere Bezeichnung

    Estrogen Receptor-alpha

    Pathways

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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