Estrogen Receptor alpha Antikörper
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- Target Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigen
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Spezifität
- Estrogen Receptor- (Ab-106) antibody detects endogenous levels of total Estrogen Receptor- protein.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from human Estrogen Receptor- around the phosphorylation site of serine 106 (S-P- SP-P-L).
- Top Product
- Discover our top product ESR1 Primärantikörper
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- Applikationshinweise
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WB: 1:500~1:1000
IHC: 1:50~1:100. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100ug/100ul.
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity." in: The Journal of biological chemistry, Vol. 280, Issue 38, pp. 33006-14, (2005) (PubMed).
: "Potentiation of human estrogen receptor alpha transcriptional activation through phosphorylation of serines 104 and 106 by the cyclin A-CDK2 complex." in: The Journal of biological chemistry, Vol. 274, Issue 32, pp. 22296-302, (1999) (PubMed).
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Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity." in: The Journal of biological chemistry, Vol. 280, Issue 38, pp. 33006-14, (2005) (PubMed).
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- Target
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Andere Bezeichnung
- Estrogen Receptor-alpha (ESR1 Produkte)
- Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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